在口腔大喉癌中重新审视食管的利用:6年前性注册表分析
Brady J Anderson1, Amy C Moreno2, Yun Qing3
1Department of Otolaryngology, University of Iowa, Iowa City, Iowa, USA.
概括
口腔癌患者现在有27%的G管率,比十年前下降了50%. 保持吞功能和跨口腔机器人手术 (TORS) 可能会减少G管的需要和持续时间.
科学领域:
- 在瘤学瘤学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术瘤学手术瘤学
背景情况:
- 患有口腔癌 (OPC) 的患者在历史上经历了由于口服摄入量受损和营养不良而导致的输卵管使用率高.
- 输卵管依赖严重影响OPC患者的生活质量和治疗结果.
研究的目的:
- 重新审视为口腔喉癌治疗的患者目前的输卵管实践.
- 确定与OPC患者胃口管 (G管) 放置的需要和持续时间相关的因素.
主要方法:
- 从2015年到2021年在一个NCI指定的综合癌症中心对潜在队列的回顾性分析.
- 使用视频光学和头癌 (PSSHN) 绩效状态尺度评估基线吞功能.
- 多变量回归分析以确定G管放置和移除的预测因素.
主要成果:
- 在924名患者中,27%的患者接受了G管,与十年前的机构率相比,这一比例减少了50%.
- 化学辐射增加了G管风险 (OR 2.78),而横口机器人手术 (TORS) (OR 0.31) 和较高的PSSHN-饮食得分 (OR 0.26) 降低了风险.
- 在晚期瘤 (T3-T4) (HR 0.52) 中,G管切除速度较慢,在较高的PSSHN-饮食得分 (HR 1.65) 中,切除速度更快.
结论:
- 对口腔癌的现代治疗方法导致G管利用率大幅下降.
- 保持基线吞功能和符合TORS的资格与较低的G管风险和更短的持续时间有关.
- 对优化营养支持和手术技术的进一步研究是有必要的,以尽量减少OPC患者的输卵管依赖.
关键词:
这是一个G-管.化学辐射的发生.食管中的食管.胃口修复术 (gastrostomy) 是一种胃口修复术.鼻胃鼻胃的情况口腔喉癌 (OPC) 是一种疾病.辐射辐射辐射辐射的辐射通过口腔的机器人手术 (TORS)更多相关视频
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