电子烟使用后的健康成年人的炎症生物标志物变化:范围审查
Shawn Boss1, Michael Bertolio1, Laura Lipke2
1Kirksville College of Osteopathic Medicine, A.T. Still University, Kirksville, Missouri, USA.
Immunity, inflammation and disease
|February 14, 2024
概括
与尼古丁一起短期使用电子烟 (EC) 可能会增加心血管和氧化应激炎症. 长期使用EC并没有显示一般炎症生物标志物的显著变化,因此需要进一步研究.
科学领域:
- 环境健康 环境健康
- 生物标志物 生物标志物
- 心肺健康 心肺健康
背景情况:
- 全球电子烟 (EC) 的使用量正在增加.
- 关于EC使用和炎症生物标志物的审查有限.
- 了解EC对炎症的影响对于公共卫生至关重要.
研究的目的:
- 为了评估健康成年人的一般,心肺和氧化压力相关的炎症生物标志物的变化,使用ECs.
- 为了对EC消费后的炎症标志物改变进行分类.
- 综合关于EC和炎症的当前文献.
主要方法:
- 使用Arksey和O'Malley框架进行了范围审查.
- 在PubMed和MEDLINE (Ovid) 数据库中进行了搜索.
- 包括全文文章,灰色文献和健康成年人的初级研究,不包括那些有混的病史的人.
主要成果:
- 37项研究符合纳入标准.
- 短期 (<1个月) 尼古丁EC使用中度增加心血管 (CV) 和氧化应激炎症标志物 (分别为50%和64%的病例).
- 长期 (>1个月) 尼古丁EC使用产生了混合的结果,在75%和60%的测量实例中分别呈现了升高的矩阵金属蛋白酶-9 (MMP-9) 和介质蛋白-6 (IL-6).
结论:
- 短期尼古丁EC使用可能会增加心血管和氧化应激炎症,可能增加心血管或神经疾病的风险.
- 长期使用尼古丁EC并没有显示一般炎症生物标志物的显著变化.
- 需要进一步的系统审查和元分析来确认发现并评估对MMP-9和IL-6的长期影响.
关键词:
生物标志物 生物标志物心血管疾病心血管疾病电子烟 (e-cig) 是一种电子烟.电子烟是一种电子烟.这是一种炎症炎症炎症炎症.氧化应激是一种氧化应激.肺部疾病是一种肺部疾病.电子烟 (vape) 是一种电子烟.更多相关视频
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