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通过微粒的逆行运动自发回收喷射样本

Ochir Ochirov¹, Pawel L Urban¹

¹Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu 300044, Taiwan.

Journal of the American Society for Mass Spectrometry

|February 14, 2024

概括

电子喷射电离 (ESI) 滴滴可以意外地向后移动,并在半月板上充电. 这种现象提高了ESI质谱学中的样本利用效率.

科学领域:

分析化学分析化学
物理化学物理化学

背景情况:

电子喷射电离 (ESI) 是质谱学中的一个关键技术.
在ESI中滴滴动态是复杂的,并影响电离效率.

研究的目的:

为了研究一个自发的反向滴滴运动现象在电喷射发射器半径附近.
了解这种现象对ESI采样利用的影响.

主要方法:

在电喷射发射器尖端观察滴水的行为.
对液滴与液体阴囊相互作用的分析.
用于ESI质谱学中常见的电解质溶液.

主要成果:

一些被弹出的滴滴减速并向后移动到半月板.
滴在半径上充电,重新加速或发射二次滴.
这种反向运动和充电在含有常见ESI添加剂的甲醇-水溶液中被观察到.

结论:

观察到的现象表明样品液体在电子喷雾剂中的回收.
这种回收机制可以显著提高ESI中的样本利用效率.
滴状电荷转移可能超过雷利极限,导致二次排放.

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