抗生素耐药性的时空空间变化,潜在的病原体,以及幼儿园灰尘健康风险
Li-Juan Li1,2, Fei Xu1,2, Jian-Xin Xu3
1Key Laboratory of Urban Environment and Health, Ningbo Observation and Research Station, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen 361021, China.
Environmental science & technology
|February 14, 2024
概括
幼儿园的灰尘含有抗生素耐药性基因 (ARG) 和病原体. 冬季和城市尘埃的含量更高,增加了健康风险,特别是当它们结合在一起时.
科学领域:
- 环境微生物学环境微生物学
- 公共卫生 公共卫生
- 分子生物学分子生物学
背景情况:
- 幼儿园中的微生物会影响儿童的健康.
- 幼儿园的室外灰尘可能会带来健康风险.
- 抗生素耐药性基因 (ARG) 和病原体越来越令人担忧.
研究的目的:
- 为了研究抗生素耐药性基因 (ARG) 和幼儿园灰尘中的潜在病原体.
- 评估对ARG和病原体的季节性和城市影响.
- 了解ARG,移动遗传元素 (MGE) 和病原体的共同发生.
主要方法:
- 从中国门59所幼儿园收集的尘埃样本 (冬季和夏季).
- 用于分析ARG的高通量定量PCR (HT-qPCR).
- 用于识别ARG,MGE和病原体的元基因组测序.
主要成果:
- 与夏季相比,冬季尘埃中观察到更高的ARG丰度和丰度.
- 城市幼儿园的ARG和潜在病原体的流行率更高.
- 同时发生的分析表明,细菌病原体经常携带ARG和MGE.
- 高风险的ARG在冬季和城市尘埃样本中更为丰富.
结论:
- 城市化和冬季条件显著增加了幼儿园灰尘中抗生素耐药性带来的风险.
- 尘埃中ARG和病原体的组合对人类健康构成重大威胁.
- 需要更加关注与环境中的ARG,MGE和病原体相关的健康风险.
更多相关视频
06:54Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
Published on: July 19, 2024
1.0K
05:45Composition and Distribution Analysis of Bioaerosols Under Different Environmental Conditions
Published on: January 7, 2019
10.7K
相关概念视频
00:57Antibiotic Selection
53.5K
Overview
53.5K
01:26Factors Affecting the Risk of Infection
11.8K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.8K
01:20Sputum Studies II: Culture and Sensitivity
322
Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
The test can identify various pathogens responsible for respiratory infections, including Streptococcus,...
322