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Updated: Jul 3, 2025

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Published on: January 22, 2019

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失败下调PI3K信号使自动反应性B细胞对旁观者T细胞敏感

Brigita E Fiske1, Andrew Getahun1,2

  • 1Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO.

Journal of immunology (Baltimore, Md. : 1950)
|February 14, 2024
PubMed
概括

T细胞的帮助对于自身抗体的产生至关重要,即使在B细胞耐受性失败时也是如此. 自主反应性B细胞中升级的PI3K信号增强了与T细胞的合作,促进了自身抗体反应.

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