后COVID-19条件的认知症状和日常功能
Abhishek Jaywant1, Faith M Gunning1, Lauren E Oberlin1
1Department of Psychiatry, Weill Cornell Medicine, New York, New York.
JAMA network open
|February 14, 2024
概括
在COVID-19后的情况中,认知症状很普遍,影响日常功能和就业. 解决这些症状对于公共卫生对长期COVID的反应至关重要.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 认知症状在COVID-19后的情况中经常被报告,但缺乏关于可概括人口中的人口统计和功能因素的全面表征.
- 了解这些因素对于有效的管理和公共卫生战略至关重要.
研究的目的:
- 为了确定后COVID-19条件的个人自我报告的认知症状的患病率.
- 为了比较认知症状患病率与急性SARS-CoV-2感染但没有COVID-19后疾病的个人.
- 检查认知症状与抑郁症状和功能状态的关联.
主要方法:
- 一个50个州,非概率,基于人口的互联网调查是在2022年12月至2023年5月之间进行的.
- 参与者包括14767名18岁以上的成年人,他们至少在两个月前报告了经过测试确认的COVID-19.
- 用Neuro-QoL认知电池评估认知症状,用患者健康问卷-9.9测量抑郁症状.
主要成果:
- 在1683名患有COVID-19后病情的人中,56.7%的人每天报告有认知症状,而没有COVID-19后病情的人中有27.1%.
- 每日认知症状与功能干扰增加 (AOR,1.30),全职就业减少 (AOR,0.92) 和抑郁症状严重程度增加 (系数,1.27) 相相关.
- 考虑到抑郁症状后,这些关联仍然很重要.
结论:
- 认知症状在COVID-19后的情况中很常见,并且与显著的功能障碍,就业减少和抑郁症状增加有关.
- 查和解决认知症状应该是公共卫生应对COVID-19后状况的一个组成部分.
- 这些发现凸显了对长期COVID患者认知功能障碍有针对性的干预措施的需要.
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