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在跨性别女性中进行前列腺癌查的普及率

Sandhya Kalavacherla^1,2, Paul Riviere^1,2, Sruthi Kalavacherla^2,3

¹Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla.

JAMA network open

|February 14, 2024

概括

与 cisgender 男人相比,跨性别女性的前列腺特异抗原 (PSA) 查率较低. 临床医生的建议显著增加了跨性别女性的PSA查,强调了医生主导的癌症预防讨论的重要性.

科学领域:

泌尿病学和瘤学泌尿和瘤学
公共卫生和预防医学
健康差距研究研究研究研究

背景情况:

前列腺特异性抗原 (PSA) 查指南对于跨性别女性缺乏共识,尽管她们已知患前列腺癌的风险.
了解影响跨性别女性PSA查的因素对于公平的癌症预防策略至关重要.

研究的目的:

确定与最近的PSA查 (2年内) 相关的因素,与 cisgender 男人相比,跨性别女性.
调查临床医生建议和讨论在PSA查跨性别女性吸收中的作用.

主要方法:

一项使用2018年和2020年行为风险因素监测系统 (BRFSS) 调查数据的病例控制研究.
纳入标准:40岁以上的 cisgender 男人和跨性别女性,没有前列腺癌史,完整的 PSA 测试数据.
多变量逻辑回归分析对255名跨性别女性和1020名 cisgender男性进行了匹配的队列.

主要成果:

近期的PSA查率在变性女性 (22.2%) 与55-69岁 cisgender男性 (36.3%) 相比较较低.
变性女性最近查的无变几率较低 (OR,0.65).
临床医生推PSA检测是与跨性别女性最近的查相关的最强因素 (OR,12.40).

结论:

获得护理和社会人口统计因素似乎不是查差异的主要驱动因素.
这些发现强调了临床医生在影响PSA查决策和跨性别女性吸收方面的关键作用.
加强临床医生的参与和推对于改善这一群体的前列腺癌查至关重要.

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