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耐性固体中的Pyroxasulfone代谢:这一切都归功于GST活动吗?

Danica E Goggin¹, Gregory R Cawthray², Roberto Busi¹

¹Australian Herbicide Resistance Initiative, School of Agriculture and Environment, University of Western Australia, 35 Stirling Highway, Crawley 6009, Australia.

Journal of agricultural and food chemistry

|February 14, 2024

概括

谷氨转移酶 (GST) 活性是麦草 (Lolium rigidum) 对除草剂pyroxasulfone产生耐药性的关键. 这种代谢途径对于杂草控制策略至关重要.

科学领域:

农业科学农业科学
植物生物化学植物生物化学
杂草科学杂草科学杂草科学

背景情况:

越来越多的杂草对像pyroxasulfone这样的除草剂的耐药性对农业构成了重大挑战.
之前的研究已经确定了谷氨转移酶 (GST) 活性作为特定的麦草种群的耐药性机制.
在Lolium rigidum中广泛存在的pyroxasulfone耐药性中,GST介导代谢的作用需要进一步研究.

研究的目的:

调查基于GST的新陈代谢作为*Lolium rigidum*中硫耐药性的机制的流行情况.
为了选多个 *Lolium rigidum* 种群,以确定 GST 介导的抗性的关键指标.

主要方法:

通过GST活动对假定耐药的*Lolium rigidum*种群进行pyroxasulfone结合的查.
分析GSTF13类异型的存在,组织中的谷氨水平,以及对GST和氧化酶抑制剂的反应.
利用随机森林分析来确定除草剂耐药性的主要驱动因素.

主要成果:

没有发现pyroxasulfone耐药水平和个人参数 (如GST活性或谷氨酸度) 之间的直接相关性.
随机森林分析发现,GST活动是导致*Lolium rigidum*中硫耐药性的最重要因素.
基于GST的除草剂代谢被认为是瑞草耐药性的关键因素.

结论:

谷氨转移酶 (GST) 活性在硬 (Lolium rigidum) 对硫 (pyroxasulfone) 的耐药性进化中发挥着关键作用.
了解GST介导的排毒对于开发有效的杂草管理策略来对抗耐药的麦草至关重要.
准GST途径可能为除草剂耐药性管理提供新的途径.

关键词:

谷氨转移酶的作用抗除草剂耐药性抗除草剂耐药性麦草麦草是一种麦草.非常长链脂肪酸延长酶抑制剂小麦小麦小麦小麦小麦小麦小麦.异生生物结合的结合方式

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