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Updated: Jul 3, 2025

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多种转录组学确定SIKE是一种MAPK抑制剂,可以防止NASH进展

Lan Bai1,2,3, Weiyi Qu3,4, Xu Cheng1,2

  • 1Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China.

Science translational medicine
|February 14, 2024
PubMed
概括

抑制IKKε (SIKE) 抑制MAP激酶 (MAPK) 激活,这是非酒精性脂肪肝 (NAFL) 进展到非酒精性脂肪肝炎 (NASH) 的关键驱动因素. 升级SIKE显示了预防和治疗NASH的前景.

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