相关实验视频

Updated: Jul 3, 2025

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy
06:51

Manufacturing Chimeric Antigen Receptor CAR T Cells for Adoptive Immunotherapy

Published on: December 17, 2019

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工程T细胞分泌抗BCMAT细胞参与者控制多发性骨髓瘤,并在体内促进免疫记忆

Laura Díez-Alonso1,2,3, Aïda Falgas4,5, Javier Arroyo-Ródenas1,2,3

  • 1Cancer Immunotherapy Unit (UNICA), Department of Immunology, Hospital Universitario 12 de Octubre, 28041 Madrid, Spain.

Science translational medicine
|February 14, 2024
PubMed
概括

与CAR-T细胞相比,分泌双特异性抗体的工程T细胞 (STAb-T) 对多发性骨髓瘤具有更高的疗效. STAb-T细胞克服了耐药性并控制了疾病的进展,为复发性/耐药性多发性髓瘤提供了有前途的新疗法.

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