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Updated: Jul 3, 2025

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定时神经发生:时钟还是算法?

Julien Pigeon1, Bassem A Hassan1

  • 1Institut du Cerveau-Paris Brain Institute (ICM), Sorbonne Université, Inserm, CNRS, Hôpital Pitié-Salpêtrière, Paris, France.

Current opinion in genetics & development
|February 14, 2024
PubMed
概括

分子机制控制神经发生的时间,由进化选择驱动. 计算机科学框架有助于理解这些大脑发育过程.

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Circadian Rhythms and Gene Regulation02:19

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The biological clock is involved in many aspects of regulating complex physiology in all animals. It was in 1935 when German zoologists, Hans Kalmus and Erwin Bünning, discovered the existence of circadian rhythm in Drosophila melanogaster. However, the internal molecular mechanisms behind the circadian clock remained a mystery until 1984, when Jeffrey C. Hall, Michael Rosbash, and Michael W. Young discovered the expression of the Per gene oscillating over a 24-hour cycle. In subsequent...
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