持续升高的开口压力,尽管治疗和症状的解决在儿科内高血压的症状解决
Lisa Pabst1, Brandon S Aylward2, David L Rogers3
1Department of Neurology, Nationwide Children's Hospital, Columbus, Ohio.
Pediatric neurology
|February 14, 2024
概括
在儿科内高血压 (PIH) 中,腰部穿孔开口压力往往在治疗后仍然很高. 临床症状和症状,而不仅仅是压力读数,应指导PIH管理和复发的确定.
科学领域:
- 神经学 神经学
- 儿科 儿科 儿科
- 眼科医生 眼科 眼科
背景情况:
- 目前还没有关于重复腰部穿刺 (LP) 治疗儿科原发性内高血压 (PIH) 的指导方针.
- 了解压力变化对于指导治疗调整和评估疾病复发至关重要.
研究的目的:
- 分析治疗期间儿科PIH患者的开口压力 (OP) 变化.
- 为了确定诊断时的OP测量是否预测疾病复发.
主要方法:
- 对儿科PIH患者 (≤18岁) 的机构数据库的回顾性审查.
- 诊断时记录开口压力,在药物断前和药物断后记录开口压力.
- 在患有和没有疾病复发的患者之间对OP测量的比较.
主要成果:
- 分析了42名患者;诊断时的平均年龄为11.01岁.
- 在诊断,断奶前和断奶后的时间点 (P=0.14) 中,打开压力没有显著差异.
- 从诊断到断奶后观察到OP显著减少 (5.18厘米H2O,P=0.04).
结论:
- 儿科PIH患者的平均开口压力在药物治疗后仍然很高,即使有已消失的乳头发和症状.
- 对光盘的症状和患者症状的临床评估对于确定PIH复发和指导治疗至关重要.
- 这项研究强调了对PIH管理采取多因素方法的必要性.
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