隐藏性肝病:一个跨国视角
Paulina Vidal-Cevallos1, Nayelli Flores-García2, Norberto C Chávez-Tapia1
1Obesity and Digestive Disease Unit, Medica Sur Clinic and Foundation, Puente de Piedra 150, Toriello Guerra, 14050, Mexico City, Mexico.
隐藏性肝病,往往没有被认可,是全球重要的健康问题. 早期查和治疗,特别是非酒精性脂肪肝 (NAFLD) 和病毒性肝炎,对于降低死亡率至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 肝病是全球第11大死亡原因,占所有死亡人数的4%.
- 酒精消费是肝硬化的主要驱动因素 (60%的病例),而非酒精性脂肪肝 (NAFLD) 患病率在全球上升 (估计为32.4%).
- 病毒性乙型肝炎和型肝炎在2020年造成了130万人的死亡,突显了传染性肝病的负担.
研究的目的:
- 为了强调隐藏性肝病的意义,定义为未被认可的慢性肝病和肝硬化.
- 突出需要评估拉丁美洲隐性肝病的流行率,该地区的代谢疾病和酒精消费率很高.
- 倡导针对性查和肝病早期干预策略.
主要方法:
- 全球肝病统计和风险因素的综述.
- 识别隐性肝病的高风险人群,包括肝酶升高,2型糖尿病和过度饮酒的人群.
- 强调对非酒精性脂肪性肝病 (NAFLD) 和酒精使用障碍的查策略.
主要成果:
- 研究表明,风险人群中隐性肝病的患病率很高.
- 拉丁美洲是需要进一步调查的关键地区,因为其代谢疾病和酒精消费率很高.
- 早期检测和干预是减轻肝病负担的关键.
结论:
- 隐藏性肝病在全球范围内代表着相当大的,往往未被发现的健康负担.
- 在高风险人群中,针对NAFLD和与酒精有关的肝病进行有针对性的查至关重要.
- 及时治疗隐性肝病,包括病毒性肝炎,可以预防进展和传播,降低整体死亡率.
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