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Updated: Jul 3, 2025

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer
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通过热挤出和双喷嘴化沉积建模3D打印开发多重结构延长释放片

Peilun Zhang1, Jinghan Li2, Eman A Ashour1

  • 1Department of Pharmaceutics and Drug Delivery, School of Pharmacy, The University of Mississippi, University, MS 38677, USA.

International journal of pharmaceutics
|February 14, 2024
PubMed
概括

这项研究成功地使用热挤出 (HME) 和3D打印制造了延长释放 (ER) 片. 这种新技术允许复杂的药物释放配置文件,展示了3D打印技术.

关键词:
通过3D打印打印3D打印.延长释放片剂 延长释放片剂化沉积物的建模.热挤出方式个性化医疗是个性化的医疗.

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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