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快眼睡眠阻塞性睡眠呼吸暂停症睡眠暂停症

Maria R Bonsignore¹, Emilia Mazzuca², Pierpaolo Baiamonte²

¹PROMISE Department, University of Palermo, Institute for Biomedical Research and Innovation (IRIB), National Research Council (CNR), Palermo, Italy mariarosaria.bonsignore@unipa.it.

European respiratory review : an official journal of the European Respiratory Society

|February 14, 2024

概括

阻塞性睡眠呼吸暂停 (OSA) 可能发生在REM睡眠期间,特别是在女性中,并且与高血压和白天嗜睡有关. 用CPAP治疗REM OSA的有效治疗坚持是具有挑战性的,需要进一步研究替代疗法.

科学领域:

睡眠医学睡眠医学
呼吸系统医学呼吸系统医学
心脏病学心脏病学

背景情况:

阻塞性睡眠呼吸暂停 (OSA) 可以在快速眼动 (REM) 睡眠期间表现出来,这一阶段的特点是由于肌肉衰竭而导致上呼吸道崩.
与REM睡眠相关的OSA (REM OSA) 事件通常比非REM (NREM) 睡眠更严重,并导致较大的氧气不和.
晚期OSA在女性中更为普遍,并且通常与基于呼吸暂停-呼吸暂停指数的轻度至中度OSA严重程度有关.

研究的目的:

审查有关REM OSA的当前文献,包括其特征,后果和治疗挑战.
对REM OSA现有研究进行批判性评估,确定未来研究的局限性和领域.

主要方法:

对REM睡眠期间阻塞性睡眠呼吸暂停的研究进行文献综述.
对有关流行率,临床关联和治疗疗效的现有数据进行批判性分析.

主要成果:

晚期OSA在女性中更为普遍,通常与轻度至中度的OSA,高血压和过度的白天嗜睡有关.
快速休眠症可能会增加心脏代谢风险,最佳的CPAP遵从性需要更长的治疗时间.
患有REM OSA的患者对CPAP的坚持不强,这表明需要替代治疗方法.

结论:

目前关于REM OSA的数据突出显示了治疗坚持的重大健康风险和挑战.
审查强调需要进一步研究有效的管理策略,包括针对REM OSA的非CPAP替代治疗方法.
了解REM OSA对于全面的睡眠呼吸暂停管理和缓解相关并发症至关重要.

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