在HPV口癌中,对效应性T细胞的CD137/Eomes激活轴的假设

Robin Baudouin1,2, Eric Tartour3, Cécile Badoual4

  • 1Department of Otolaryngology-Head & Neck Surgery, Foch Hospital, 40 rue Worth, 92 150, Suresnes, France. robin.baudouin@aol.com.

概括

慢性人类乳头瘤病毒 (HPV) 感染导致口腔癌. 调节性T细胞 (TREG) 矛盾地改善了HPV阳性口支状状细胞癌 (HPV+OSC) 的预后,这表明了一种涉及CD137和Eomes的新型作用因子通路.

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