Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Stomach Histology01:26

Stomach Histology

1.2K
The stomach comprises several layers that work together to facilitate digestion and protect the organ. The outermost layer is called the serosa, which provides support and protection to the stomach. The muscularis externa layer is responsible for the mechanical breakdown of food by contracting and moving the stomach. The submucosa layer, located beneath the muscularis externa, contains connective tissue, blood vessels, nerves, and glands that secrete mucus and other substances essential for...
1.2K
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

71.2K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
71.2K
Histology of the Gastrointestinal (GI) Tract01:20

Histology of the Gastrointestinal (GI) Tract

1.0K
The GI tract, from beginning to end, is made up of four continuous tissue layers that adjust their structure according to their specific roles. These layers, from innermost to outermost, are known as the mucosa, submucosa, muscularis, and serosa, which are continuous with the mesentery.
The mucosa is sometimes called a mucous membrane due to its mucus-secreting features. This membrane is composed of epithelium, which directly interacts with ingested substances, and the lamina propria, a layer...
1.0K
Hormones Secreted by the Stomach01:25

Hormones Secreted by the Stomach

555
Enteroendocrine cells, accounting for only 1% of stomach epithelial cells, play a significant role in digestion and are classified by their digestive hormone secretions.
Each of these hormones secreted by different enteroendocrine cells plays a unique role in digestion. Here are a few examples:
555

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A human pan-disease blood atlas of the circulating proteome.

Science (New York, N.Y.)·2025
Same author

Factor XII-driven coagulation traps bacterial infections.

The Journal of experimental medicine·2025
Same author

Application of the estimand framework for an emulated trial using reference based multiple imputation to investigate informative censoring.

BMC medical research methodology·2024
Same author

Assessment of Involuntary PFM Contractions in Comparison with Existing Literature and IUGA/ICS Terminology Reports.

International urogynecology journal·2024
Same author

Global Transcriptome Analysis Reveals Distinct Phases of the Endothelial Response to TNF.

Journal of immunology (Baltimore, Md. : 1950)·2023
Same author

Author Correction: Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism.

Nature communications·2023

相关实验视频

Updated: Jul 3, 2025

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights
08:23

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights

Published on: June 28, 2024

773

一种人类胃细胞类型的转录组 (transcriptome) 亚特拉斯.

S Öling1, E Struck1, M Noreen-Thorsen1

  • 1Department of Clinical Medicine, Translational Vascular Research, The Arctic University of Norway, 9019, Tromsø, Norway.

BMC biology
|February 14, 2024
PubMed
概括

研究人员使用RNA测序数据确定了胃细胞类型的基因表达特征. 这项研究揭示了与胃癌和男性特异性主要细胞标记物相关的新型基因,从而推进了对胃生物学的理解.

关键词:
大量的RNAseqq.细胞概况分析 细胞概况分析基因丰富是一种基因丰富.胃 胃是指胃的部分.

更多相关视频

Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach
08:45

Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach

Published on: January 26, 2024

1.4K
Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas
09:08

Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas

Published on: May 31, 2012

56.1K

相关实验视频

Last Updated: Jul 3, 2025

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights
08:23

Author Spotlight: Integrating Single-Cell Transcriptomics with Organoid Cultures for Advanced Research and Therapeutic Insights

Published on: June 28, 2024

773
Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach
08:45

Author Spotlight: Generation of and Comparison Between Patient-Derived Gastric Organoids from Different Regions of the Stomach

Published on: January 26, 2024

1.4K
Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas
09:08

Production of Tissue Microarrays, Immunohistochemistry Staining and Digitalization Within the Human Protein Atlas

Published on: May 31, 2012

56.1K

科学领域:

  • 胃肠道学和分子生物学
  • 基因组学和生物信息学

背景情况:

  • 了解细胞类型特定的基因表达对人类健康和疾病至关重要.
  • 胃的独特环境和功能在细胞基因表达水平上并没有得到充分的描述.
  • 主要的单细胞测序地图书缺乏详细的胃细胞类型基因丰富特征.

研究的目的:

  • 为了预测人类胃细胞类型的转录组签名.
  • 在胃中识别细胞类型丰富基因.
  • 探索与胃癌和性别特异性差异相关的基因表达特征.

主要方法:

  • 使用了整合性相关性分析方法.
  • 分析了359个个人的未分离的胃RNA测序数据.
  • 分析了多种胃细胞类型,包括状细胞,首席细胞和免疫细胞.

主要成果:

  • 在人体胃中鉴定了1600多种细胞类型丰富基因.
  • 特征转录组签名的表层,首席,胃粘液,肠内分泌,线粒体,内皮细胞,纤维细胞,巨细胞,中性细胞,T细胞和血细胞.
  • 发现了与胃癌进展相关的非编码基因的细胞类型表达特征.

结论:

  • 这项研究为了解人类胃生物学提供了全面的路线图.
  • 通过基于性别的子集分析,确定了一组仅为男性的首席细胞丰富基因小组.
  • 发现了与胃癌和特定性别的胃细胞功能相关的新型基因表达见解.