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Updated: Jul 3, 2025

Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants
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白血病干细胞激活血统不适当的信号通路,以促进它们的生长

Sophie G Kellaway1,2, Sandeep Potluri3, Peter Keane3,4

  • 1Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK. Sophie.Kellaway@nottingham.ac.uk.

Nature communications
|February 14, 2024
PubMed
概括

在急性髓性白血病 (AML) 中,静止性白血病干细胞 (LSC) 可以导致复发. 异常的VEGF和IL-5信号在t(8;21) AML LSCs允许它们重新进入细胞循环并触发疾病复发.

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