在无法分类的间歇性肺病中,通过支气管肺冷活检后的低出血率
John Taverner1,2,3, Carmen M Lucena4, Justin L Garner1,2,5
1Royal Brompton and Harefield Hospitals, London, UK.
概括
支气管透气支气管肺冷活检 (TBLC) 是有效的诊断间歇性肺病 (ILD). 引力支气管切除和肥胖与TBLC期间出血风险增加有关.
科学领域:
- 肺部病理学 肺部病理学
- 干预性肺病学 干预性肺病学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 支气管透气支气管肺冷活检 (TBLC) 是手术肺活检的推替代方案,用于诊断不可分类的间歇性肺病 (ILD).
- 结核癌后出血的发生率有所变化,需要进一步调查其危险因素和严重程度.
研究的目的:
- 描述TBLC后临床显著出血的发生率,严重程度和危险因素.
- 评估其他并发症和TBLC在未分类ILD中的诊断收益率.
主要方法:
- 一个回顾性队列研究的成人门诊患者与不可分类的ILD谁接受了TBLC.
- 数据是在2016年7月至2021年12月期间在英国单一中心收集的.
- 在全身麻醉下进行的TBLC,使用光镜指导和预防性内支气球.
主要成果:
- 7.9%的患者出现了显著的出血,与引支气管切除,UIP组织学和中大血管有关.
- 肥胖 (BMI ≥30) 和引支气管切除预测出血时间更长.
- 肺胸发生在7.1%的人群中,30天死亡率为0%,诊断收益率为80.6%.
结论:
- 在经验丰富的中心中,TBLC表现出可接受的安全性.
- 放射性引支气管和肥胖是TBLC后出血的重要危险因素.
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