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Updated: May 5, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
10:17

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

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变异效应的综合多重测定揭示了catechol-O-methyltransferase基因表达的决定因素

Ian Hoskins1, Shilpa Rao1, Charisma Tante1

  • 1Department of Molecular Biosciences, University of Texas at Austin, Austin, TX, 78712, USA.

Molecular systems biology
|February 15, 2024
PubMed
概括

我们开发了一种新的多重测试法,以测量遗传变异如何影响从RNA到蛋白质的基因表达. 这种方法揭示了成千上万种影响catechol-O-methyltransferase (COMT) 表达水平的变异.

关键词:
科姆特 (COMT) 是一个有价值的项目.这就是MAVE的原因.突变发生是突变发生的.RNA二次结构 RNA二次结构核糖体负荷 核糖体负荷

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