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孕妇的唾液度及其与状态和甲状腺功能相关
Shaohan Li1, Wenxing Guo1, Qi Jin1
1Department of Nutrition and Food Hygiene, School of Public Health, Tianjin Medical University, Tianjin, 300070, China.
European journal of nutrition
|February 15, 2024
概括
唾液度 (SIC) 可以帮助评估孕妇的营养. 低SIC (<176μg/L) 表示缺乏,而高SIC (>529μg/L) 表示过多和甲状腺功能障碍.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 对于甲状腺激素的合成至关重要,对母亲和胎儿的健康至关重要.
- 评估孕妇的状况对于预防缺乏和过量相关的并发症至关重要.
- 唾液度 (SIC) 之前没有被研究用于评估怀孕期间的营养.
研究的目的:
- 为了确定SIC和营养状况指标在孕妇之间的关系.
- 调查使用SIC用于评估怀孕期间营养的可行性.
- 在孕妇人群中建立唾液值的参考范围.
主要方法:
- 从2021年7月到2022年12月,招募了609名孕妇的队列.
- 收集了唾液,尿液和血液样本,以测量水平和甲状腺功能.
- 随机集群采样用于参与者选择.
主要成果:
- 中位数SIC为297μg/L,与尿点度 (SUIC),24小时尿度 (UIC),24小时尿分泌量 (UIE) 和估计的摄入量 (EII) 有正相关.
- 低SIC (<176μg/L) 与缺乏症和甲状腺功能障碍的风险增加有关 (分别为2.07和2.71).
- 高SIC (>529μg/L) 与过度状态和甲状腺功能障碍 (OR=2.82和3.04,分别) 的风险增加有关.
结论:
- 在孕妇中,SIC与尿液中水平和甲状腺功能有显著的关联.
- <176μg/L和>529μg/L的SIC值可能表明缺乏和过量,以及甲状腺功能障碍.
- SIC显示出作为对孕妇营养评估的参考指标的潜力,需要进一步验证.
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