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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

524
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
524

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相关实验视频

Updated: Jul 3, 2025

Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis
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Author Spotlight: Standardizing Mouse In Vivo PET Imaging with Body Conforming Molds and Automated Analysis

Published on: October 25, 2024

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人工智能在免疫治疗中的PET/SPECT成像

Jeremy P McGale1, Delphine L Chen2,3, Stefano Trebeschi4,5

  • 1Department of Radiology, New York-Presbyterian Hospital, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. jm4782@cumc.columbia.edu.

European radiology
|February 15, 2024
PubMed
概括
此摘要是机器生成的。

应用于PET/SPECT成像的人工智能 (AI) 显示出指导癌症免疫治疗的前景. 人工智能模型分析成像特征,以预测患者的预后和瘤表型,帮助治疗决策.

关键词:
人工智能的人工智能是人工智能.免疫治疗是一种免疫疗法.定子发射断层扫描 (PET) 是一种定子发射断层扫描.单光子发射计算机断层扫描.

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PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
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科学领域:

  • 在瘤学瘤学.
  • 放射学 放射学是一门学科.
  • 人工智能的人工智能

背景情况:

  • 免疫疗法已经改变了癌症治疗,但预测患者的反应和副作用仍然具有挑战性.
  • 传统的成像方法可能无法完全捕捉免疫治疗患者的反应模式.
  • 需要先进的工具来评估治疗疗效和预测结果.

研究的目的:

  • 调查人工智能 (AI) 在正子发射断层扫描 (PET) 和单光子发射计算机断层扫描 (SPECT) 对接受免疫治疗的患者成像中的作用.
  • 审查AI模型是如何使用医学成像来开发的,用于癌症免疫治疗中的预测应用.

主要方法:

  • 对MEDLINE,CENTRAL和Embase数据库进行了范围审查.
  • 搜索术语包括免疫疗法,PET/SPECT成像和AI/放射学.
  • 数据是从2022年10月12日发布的相关文章中提取的.

主要成果:

  • 从217篇已识别的文章中选择了24篇相关研究.
  • 研究的主要瘤类型是肺,淋巴瘤和黑色素瘤.
  • 使用放射学或对PET/SPECT图像进行深度学习的AI模型主要用于预后和瘤表型.
  • 大多数研究 (75%) 包括AI模型验证.

结论:

  • 使用PET/SPECT成像的人工智能引导的方法显示出优化免疫治疗管理的潜力.
  • 在临床实施之前,需要在大型,有前景的多中心队列中进行进一步的验证.
  • 从基线成像构建的AI模型可以预测免疫治疗患者的预后和瘤表型.