在患有甲状腺功能障碍的患者中,骨肌肉和左心室质量之间的关联
Zhenchao Liu1, Guang Liu2, Yanzhi Wang3
1Institute of Integrative Medicine, Qingdao University, Qingdao, Shandong, China.
Frontiers in endocrinology
|February 15, 2024
概括
患有甲状腺功能障碍的患者经历了骨肌肉质量和左心室质量 (LVM) 的减少. 骨肌肉质量指数 (SMI) 和手握强度与LVM相关,这表明肌肉缩和心脏重塑之间存在联系.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
- 肌肉生理学 肌肉生理学
背景情况:
- 甲状腺功能障碍与显著的代谢变化有关.
- 心脏重塑和肌肉缩可以同时发生在内分泌系统疾病中.
研究的目的:
- 在甲状腺功能高的患者中,研究骨肌肉质量和左心室质量 (LVM) 之间的关系.
- 为了解肌肉缩和心脏重塑之间的相互作用提供基础.
主要方法:
- 对136名甲状腺过高患者和50名对照人群的回顾性分析.
- 将甲状腺功能高的患者分为高和低的 LVM 组.
- 多重线性回归和通用线性模型来评估相关性.
主要成果:
- 与对照组相比,甲状腺功能高的患者表现出较低的LVM,骨肌量 (SMM) 和骨肌量指数 (SMI).
- 在高 LVM 组中观察到更高的 SMI,SMM 和手握力.
- SMI和手握强度与LVM有显著的相关性.
结论:
- 甲状腺功能障碍症可能导致LVM和骨肌肉同时减少.
- 在这些患者中,LVM与SMM和手握强度相关.
- 这些发现支持进一步研究甲状腺功能障碍症中萨尔科佩尼亚和心脏病理.
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