从COVID-19中康复后的阴道功能
M G Kaya1, R Alanli2, M B Kucukay2
1Lokman Hekim University, Faculty of Medicine, Ankara Hospital, Department of Endocrinology and Metabolism, Ankara, Turkey.
概括
COVID-19幸存者通常保持正常的垂体功能和下丘脑垂体上腺 (HPA) 轴活动. 在轻度至中度病例中,COVID后症状与垂体腺功能障碍无关.
科学领域:
- 内分泌学 在内分泌学.
- 传染性疾病 传染性疾病
- 内部医学 内部医学
背景情况:
- COVID-19可能会影响内分泌功能,包括垂体腺.
- COVID-19对下丘脑垂体上腺 (HPA) 轴的影响需要进一步调查.
研究的目的:
- 评估COVID-19感染后个体的垂体腺功能.
- 具体评估COVID-19后的HPA轴的完整性.
主要方法:
- 研究了50名COVID-19幸存者和49名对照者的队列.
- 使用1μg的ACTH (Synacthen) 进行了上腺刺激测试.
- 测量了早晨血清皮质醇,ACTH,IGF-1和TSH水平.
主要成果:
- 两组之间没有观察到基线垂体激素水平的显著差异.
- 在14%的COVID-19患者中发现了低血清ACTH;4%需要刺激测试.
- 胰岛素样生长因子-1 (IGF-1) 在14%的患者中低,TSH在10%的患者中轻微升高.
结论:
- 轻度至中度的COVID-19似乎不会损害基底垂体激素水平或HPA轴功能.
- 在这个队列中,观察到的COVID后症状与垂体腺功能障碍无关.
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