型肝炎中的肝病:临床表现,与发病率的关联以及对结果的影响
Rishabh Chauhan1, Sohaib Ahmad1, Chandan Goyal1
1Internal Medicine, Himalayan Institute of Medical Sciences, Swami Rama Himalayan University, Dehradun, IND.
Cureus
|February 15, 2024
概括
肝功能障碍在草伤寒中很常见,但不会使患者的结果恶化. 这项研究发现,肝损伤与发烧缓解有关,但死亡率没有增加.
科学领域:
- 热带医学 热带医学
- 传染性疾病 传染性疾病
- 肝病学 肝病学是一种肝病学.
背景情况:
- 急性肝损伤是热带发烧的已知并发症,包括草伤寒.
- 了解型肝炎肝损伤的程度和影响对于患者管理至关重要.
研究的目的:
- 为了评估皮伤寒患者肝损伤的患病率和严重程度.
- 评估肝损伤与草伤寒病的严重程度和患者结局之间的关联.
主要方法:
- 一个单一的中心,前性,观察性研究是对北印度住院的草伤寒患者进行的.
- 根据转氨酶水平对患者进行分类,以评估肝功能,并对肝损伤的严重程度进行分类 (轻度至非常严重).
- 临床参数,疾病严重程度标志物和结局与肝损伤有关的结果被分析.
主要成果:
- 肝功能障碍在76%的患者中被观察到,并且与,肝大和大有关.
- 肝病与冲击,和呼吸系统不全以及重症监护室入院有显著的相关性.
- 虽然死亡率相似,但肝损伤患者经历了延迟的发热 (发烧解消).
结论:
- 肝功能障碍在草原伤寒中普遍存在,并与特定的临床症状和疾病严重程度有关.
- 尽管肝损伤严重程度增加,但住院时间和死亡率等结果没有显著影响.
- 这项研究表明,草伤寒的肝功能障碍并不一定导致患者的预后较差.
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