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在接受全关节整形术的老年患者中,不同血液储存技术的影响的比较

Yuanxing Cai¹, Xin He¹, Qinghao Cheng¹

¹Department of Anesthesiology, Emergency General Hospital, Beijing, China.

African health sciences

|February 15, 2024

概括

与自身输血 (ABT) 相比,急性异体血稀释 (ANH) 在老年关节置换患者中改善了术后凝血和减少了血小板激活. 在THA手术中,ANH为血液节约提供了更好的结果.

科学领域:

整形外科手术整形外科手术
麻醉学麻醉学
输血医学输血医学

背景情况:

接受全关节整形术 (THA) 的老年患者有患术后并发症的风险.
血液保存技术对于在THA期间管理血液损失至关重要.
评估不同的血液保存方法对于优化患者的治疗结果至关重要.

研究的目的:

为了比较自身输血 (ABT) 和急性异体血稀释 (ANH) 对凝血功能的影响.
评估这些技术对接受THA的老年患者预后的影响.
为了确定THA的最佳血液保护策略.

主要方法:

这是一项随机对照试验,涉及60名接受THA治疗的老年患者.
第1组:自主输血 (ABT) 使用手术内血液回收和处理.
第二组:急性异体血稀释 (ANH) 与手术前抽血和体积替换.

主要成果:

在手术后48小时,ANH组的血红蛋白水平显著上升.
激活的部分血栓形成时间 (APTT) 在ANH组较短.
在ANH组中观察到血小板激活标志物CD62P的表达较低.

结论:

在维持术后血红蛋白水平和改善凝血参数方面,ANH优于ABT.
与THA患者的ABT相比,ANH降低了血小板激活.
虽然ANH在血液保存和凝固方面显示出好处,但住院时间在各组之间没有显著差异.

关键词:

关节整形术关节整形术它是自主性的,自主性的.输血输血输血输血输血血液稀释是指血液稀释.血小板激活因子血小板激活因素输血红细胞的输血.

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