在患有神经纤维素瘤类型1儿童的眼科发现
Caroline Maria Zimmermann1, Shonar Singh2, Nur Cardakli2
1Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Neuro-ophthalmology (Aeolus Press)
|February 15, 2024
概括
患有1型神经纤维素瘤 (NF1) 和视通路质瘤 (OPG) 的儿童视力敏度降低,视网膜神经纤维层 (RNFL) 较薄. 这项纵向研究突出了OPGs.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学是一种遗传学.
- 儿科 儿科 儿科
背景情况:
- 神经纤维素瘤类型1 (NF1) 是一种具有可变表达性的遗传性疾病.
- 在NF1中,眼部表现很常见,包括光通路质瘤 (OPG).
研究的目的:
- 为了评估NF1.1儿童的眼科发现.
- 为了比较NF1患者的眼睛发现,有和没有OPG.
主要方法:
- 对119名患有NF1.1的儿童进行了回顾性图表审查.
- 眼科发现的分析,包括视敏度,眼内压力和光学连贯性断层扫描 (OCT).
- 具有和没有OPG的眼睛之间的发现结果的比较.
主要成果:
- 常见的NF1表现包括咖啡牛奶斑块和利希结节.
- 23%的参与者患有OPG,影响了44只眼睛.
- 有OPG的眼睛在最终检查时显示视觉敏度更差,视网膜神经纤维层 (RNFL) 更薄.
结论:
- OPG与NF1.1儿童的视觉结果较差有关.
- 纵向跟踪显示,RNFL与OPG在眼睛中的显著稀释.
关键词:
1型神经纤维素瘤病的一种类型.磁共振成像技术的使用视觉通路的质瘤 视觉通路的质瘤光学连贯性断层扫描 (optical coherence tomography) 是一种光学连贯性断层扫描技术.儿科 儿科 儿科更多相关视频
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