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Updated: Jul 3, 2025

Detection of a CDH1 Rare Transcript Variant in Fresh-frozen Gastric Cancer Tissues by Chip-based Digital PCR
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分裂的PCDH9的核转位通过降低CDH2表达的调节,损害胃癌转移

Yajuan Zhang1,2, Yingwei Zhu3, Ying Chen4

  • 1Shanghai Institute of Thoracic Oncology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.

iScience
|February 15, 2024
PubMed
概括

丢失Protocadherin 9 (PCDH9) 通过增加Cadherin 2 (CDH2) 的DNA甲基化,损害胃癌转移. 核PCDH9与DNMT1相互作用,降低CDH2的调节,影响患者的预后.

关键词:
生物化学 生物化学生物科学 生物科学癌症 癌症 癌症 癌症细胞生物学 细胞生物学自然科学 自然科学

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