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在体外和体内模型定义了人类胚胎细胞的分子签名参考

Julie Warin1, Nicolas Vedrenne1,2, Vivian Tam3

  • 1Nantes Université, Oniris, CHU Nantes, Inserm, Regenerative Medicine and Skeleton, RMeS, UMR 1229, 44000 Nantes, France.

iScience
|February 15, 2024
PubMed
概括

研究人员开发了一种新方法,可以从多能干细胞 (PSC) 产生人体心弦细胞 (NC). 这项研究确定了关键的分子标记物,并改善了用于再生医学应用的NC生成.

关键词:
生物科学 生物科学人类发展生物学 人类发展生物学发育生物学是发展生物学.自然科学 自然科学俄米克斯 (Omics) 是一个电子游戏.文字转录学 (Transcriptomics) 是一个学科.

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相关概念视频

Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In...
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