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Fabrication of Micropatterned Hydrogels for Neural Culture Systems using Dynamic Mask Projection Photolithography
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采用深度网络幻觉,切出一个甘氨酸酶活性站点,将其纳入一个新的蛋白质支架中

Anders Lønstrup Hansen1, Frederik Friis Theisen1, Ramon Crehuet2

  • 1The Linderstrøm-Lang Centre for Protein Science, Section for Biomolecular Sciences, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen, Denmark.

ACS synthetic biology
|February 15, 2024
PubMed
概括

计算设计创造了简化的酶支架,减少了尺寸并保持了稳定性. 这为未来的酶工程和工业应用提供了一个有希望的基础.

关键词:
这是一个de novo设计.深度网络 幻觉 幻觉酶设计 酶设计葡萄糖酸酸酶是什么 葡萄糖酸酸酶是什么

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相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...