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相关概念视频

Phase Contrast and Differential Interference Contrast Microscopy01:26

Phase Contrast and Differential Interference Contrast Microscopy

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Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...
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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
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相关实验视频

Updated: Jul 3, 2025

Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing
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Multimodal Quantitative Phase Imaging with Digital Holographic Microscopy Accurately Assesses Intestinal Inflammation and Epithelial Wound Healing

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实现一个便携式衍射相位显微镜用于数字组织病理学.

Nurbolat Aimakov1, Eunjung Min2, Sungbea Ban1

  • 1Department of Biomedical Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.

Journal of biophotonics
|February 15, 2024
PubMed
概括

一种便携式衍射相位显微镜 (DPM) 系统为组织病理学提供了未染色的定量相位成像. 这种紧的DPM系统提供了与基板系统相当的性能,并通过深度学习实现虚拟染色.

科学领域:

  • 生物医学光学 生物医学光学
  • 数字病理学数字病理学
  • 定量的相位成像成像技术

背景情况:

  • 定量相成像 (QPI) 提供了对生物组织的无标签可视化,这对组织病理学至关重要.
  • 开发紧和便携式QPI系统可以提高各种研究应用的可访问性.
  • 衍射相位显微镜 (DPM) 是一种QPI技术,捕捉相位移动以可视化未染色的生物结构.
关键词:
分散相显微镜的微镜.定量阶段成像成像技术的使用.虚拟染色是一种虚拟染色.

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Last Updated: Jul 3, 2025

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