单剂量埃诺沙巴林用于袖子胃切除术后的口腔腹膜静脉血栓症预防
Mohammad Nebih Nofal1, Waleed I Wadi2, Ali J Yousef1
1Department of General Surgery and Anesthesia, Faculty of Medicine, Mutah University, Karak, Jordan.
Annals of African medicine
|February 15, 2024
概括
单次术后剂量的埃诺沙巴林有效地预防了腹腔镜袖子胃切除术 (LSG) 后的腹腔门静脉血栓症 (PMVT). 这种方法显示PMVT发病率低,为0.85%,而不会增加出血风险.
科学领域:
- 腹部外科 腹部外科
- 血管外科 血管外科
- 药理学 药理学是指药理学的学科.
背景情况:
- 门中静脉血栓形成 (PMVT) 是袖子胃切除术后的一种潜在并发症.
- 在减肥手术患者中,PMVT的预防策略至关重要.
研究的目的:
- 评估单次术后剂量埃诺沙巴林在腹腔镜袖子胃切除术 (LSG) 后预防PMVT的疗效.
- 为了比较单剂量埃诺沙巴林预防的结果与PMVT预防的其他外科手术期间的预防方案.
主要方法:
- 对590名接受LSG的患者进行了回顾性队列研究.
- 从医疗病历中收集的数据,在手术后的18个月内定期进行随访.
- 描述性统计分析以确定PMVT发病率,单次40毫克皮下注射埃诺沙巴林剂量.
主要成果:
- 该研究包括590名在2017年1月至2021年12月期间接受LSG的患者.
- 5名患者 (0.85%的发病率) 患有PMVT.
- 相关并发症包括心动减速 (3名患者) 和手术后出血 (3名患者).
结论:
- 在LSG患者中,单次术后剂量40毫克埃诺沙巴林是有效的血栓形成预防.
- 这种疗法似乎不会增加术后出血的风险.
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