在B型淋巴细胞白血病病例中,涉及骨髓和皮肤的系统性桑托格兰瘤
Manasi C Mundada1, Faiq Ahmed1, Suseela Kodandapani1
1Department of Laboratory Medicine, Basavatarakam Indo American Cancer Hospital, Banjara Hills, Hyderabad, Telangana, India.
Indian journal of pathology & microbiology
|February 15, 2024
概括
青春期桑托格拉努隆瘤通常影响儿童.
科学领域:
- 皮肤病学 皮肤病学
- 儿科 儿科 儿科
- 病理学 病理学 病理学
背景情况:
- 青少年桑托格兰瘤 (JXG) 是婴儿和儿童常见的良性皮肤疾病.
- 它通常呈现为皮肤上的黄色棕色斑块.
- JXG通常是自我限制的.
研究的目的:
- 描述青少年桑托格兰瘤的诊断特征.
- 突出特定临床环境中的诊断挑战.
主要方法:
- 病变的组织形态学检查.
- 免疫组织化学分析 (CD68,CD163,XIIIa因子,CD1a,S-100).
主要成果:
- 经典的基因病理学显示皮肤上具有特定细胞特征的基因细胞聚合物.
- 免疫组织化学证实了囊细胞的起源,并有助于分化.
结论:
- 诊断通常是基于临床和组织病理学发现的简单.
- 骨髓参与后B型淋巴细胞白血病存在诊断困难.
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