童年不良经历和青春期早期身体疼痛之间的关联
Armine Abrahamyan1,2, Raquel Lucas1,2, Milton Severo1,2
1EPIUnit - Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
概括
儿童暴露于不良童年经历 (ACE) 显著预测了青春期早期的疼痛. 早期的逆境是晚年慢性疼痛发展的关键因素.
科学领域:
- 儿科 儿科 儿科
- 心理学 心理学 心理学
- 流行病学 流行病学
背景情况:
- 儿童不良经历 (ACE) 与长期健康问题有关.
- 了解青少年疼痛的早期预测因素对于干预至关重要.
研究的目的:
- 调查儿童早期终身暴露在ACE和青春期疼痛特征之间的关联.
- 为了确定早期的ACE是否预测青少年疼痛发作,即使考虑到以后的逆境.
主要方法:
- 4564名青少年的前性队列研究 (第21代出生队列).
- 在10岁和13岁时使用15项问卷评估ACE.
- 疼痛特征 (任何疼痛,疼痛部位,强度,持续时间) 在13岁时通过结构化问卷测量.
主要成果:
- 在10岁时ACE和13岁时任何疼痛之间发现了显著的关联 (OR=1.09).
- 这种关联仍然显著 (aOR=1.11) 即使在对13岁时报告的ACE进行调整后.
- 对疼痛部位,强度和持续时间观察到类似的模式,表明ACE预测了各种疼痛特征.
结论:
- 童年暴露在逆境中是青春期早期疼痛特征的重要预测因素.
- 生命的第一个十年中的ACE代表了慢性疼痛发展的关键途径.
- 早期的生活逆境应该被认为是青少年疼痛病因的关键风险因素.
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