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在血清阳性和血清阴性自身免疫脑炎中语言障碍

Sarah P Griffith^1,2, Robb Wesselingh^1,2, Fiore D'Aprano³

¹Department of Neurosciences, Central Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Level 6, Alfred Centre, 99 Commercial Road, Melbourne, VIC, 3004, Australia.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

|February 15, 2024

概括

虽然自身免疫性脑炎患者通常平均具有正常的语言功能,但有些人在命名和语义流方面存在缺陷. 对于慢性病例,需要进一步研究发作负担和药物效应.

科学领域:

神经免疫学神经免疫学
认知神经学认知神经学
神经心理学神经心理学

背景情况:

自身免疫性脑炎 (AE) 是一种罕见的神经炎症疾病,影响中枢神经系统.
了解AE中的语言功能对于患者管理和康复至关重要.

研究的目的:

研究自身免疫性脑炎 (AE) 患者的语言能力.
为了比较血清阳性和血清阴性AE患者群体之间的语言功能.

主要方法:

52名AE患者接受了标准化的语言评估,包括命名,语义流,词汇和相似性.
使用统计分析将性能与规范数据进行了比较.

主要成果:

平均而言,语言测试成绩在AE队列的正常范围内.
然而,在视觉对抗命名 (SydBat) 和语义流性 (COWAT动物) 的个人水平上观察到显著的损伤率.

结论:

一部分AE患者表现出语义流性受损和视觉对抗命名,尽管平均语言功能看起来正常.
未来的研究应该探讨在慢性AE语言缺陷中的负担和抗药物等因素.

关键词:

自身免疫性脑炎的发生.认知认知是一种认知.语言语言语言语言神经免疫学神经免疫学神经心理学神经心理学

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Language and Cognition

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.