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Updated: Jul 3, 2025

Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics
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Isolation and Characterization of a Head and Neck Squamous Cell Carcinoma Subpopulation Having Stem Cell Characteristics

Published on: May 11, 2016

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ARID1A 损失与人体头部和部状细胞癌中NRF2信号的增加有关

Vinh Nguyen1,2, Travis P Schrank1,3, Michael B Major1,4

  • 1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America.

PloS one
|February 15, 2024
PubMed
概括

在癌症中,SWI/SNF复合体和KEAP1-NRF2通路的突变与癌症有关. 在头癌中ARID1A的失活会激活NRF2信号,促进瘤的生长.

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