1996年至2021年间,伊朗伊斯法罕多发性硬化症的流行和发病率:基于人口的研究
Mahdi Barzegar1, Saeed Vaheb2, Omid Mirmosayyeb1
1Department of Neurology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Multiple sclerosis and related disorders
|February 15, 2024
概括
伊斯法罕的多发性硬化症 (MS) 发病率从1996年至2015年大幅增加,然后稳定下来. 伊斯法罕的MS率很高,在2021年患病率达到183.9/100,000.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
背景情况:
- 最近关于伊斯法罕多发性硬化症 (MS) 的流行病学数据有限.
- 需要在一个大而稳定的人口中进行全面的发病率和流行率研究.
研究的目的:
- 为了估计伊斯法罕省MS的发病率和流行率.
- 从1996年到2021年分析MS发病率和发病年龄的趋势.
主要方法:
- 使用伊斯法罕医学科学大学数据集进行基于人口的研究.
- 包括所有被诊断为多发性硬化症患者 (PDWM),不包括卡山居民.
- 粗略的发病率和流行率的测量,按性别和发病年龄分层.
主要成果:
- 多发性硬化症的发病率从5.4/100,000 (1996-2000年) 增加到71.8/100,000 (2016-2021年).
- 患病率在2021年达到183.9/100,000;儿童,成人和晚发性MS的年龄标准化发病率在2016年分别为1.8,31.4和17.5/100,000.
- 女性/男性比率从4.5下降到2.9;RRMS发病的平均年龄在2010-2019年增加到32.8.
结论:
- 伊斯法罕是该地区MS发病率和流行率最高的城市之一.
- MS发病率最初增加,然后在最近几年稳定下来.
- 需要进一步的研究来确定伊朗MS发病率变化的原因.
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