基于Au@Ag-Au的SO2蒸气的Ratiometric SERS量化,使用拉曼报告器作为内部标准
Yu Lu1, Xiufang Mo1, Geng Zhu1
1State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing 211189, China; Institute of Biomaterials and Medical Devices, Southeast University, Suzhou 215163, China; Southeast University Shenzhen Research Institute, Shenzhen 518000, China.
Journal of hazardous materials
|February 15, 2024
概括
一个新的比度表面增强拉曼散射 (SERS) 传感器提供可重复和定量检测二氧化硫 (SO2) 气体. 这一进步通过精确测量SO2残留物,使得传统中医 (TCM) 的精确质量控制成为可能.
科学领域:
- 纳米材料科学 科学 纳米材料科学
- 分析化学 分析化学
- 化学传感器 化学传感器
背景情况:
- 传统的表面增强拉曼散射 (SERS) 传感器因"热点"分布和测量条件的变化而难以复制和量化.
- 精确量化分析物,如二氧化硫 (SO2),对于实际的气体传感应用至关重要,特别是在中国传统医学 (TCM) 的质量控制中.
研究的目的:
- 开发一个依赖比率的SERS传感器,用于定量,无标签的气体传感,具有更好的可重复性和准确性.
- 为了使在TCM中使用新型SERS基板和内部标准精确量化SO2残留量.
主要方法:
- 在阳性氧化 (AAO) 上使用金-银-金 (Au@Ag-Au) 纳米颗粒制造一种新的SERS基底.
- 封装4-mercaptobenzoic酸 (4-MBA) 作为一个内部标准 (IS) 在Au@Ag-Au纳米粒子间隙.
- 头部空间采样与SO2提取和检测的比度SERS传感器的集成.
主要成果:
- 使用4-MBA作为IS开发的Au@Ag-Au@AAO SERS基质显示出使用强度比I613 cm−1/I1078 cm−1.0的SO2定量 (0.5500 mg/kg) 的优异线性.
- 传感器达到0.05 mg/kg的低检测极限,远低于中国药典规定的10 mg/kg极限.
- 在现场,使用手持式拉曼光谱仪成功实现了TCM中SO2残留的定量质量评估.
结论:
- 分度SERS传感器为SO2检测提供了高度灵敏,可重复和定量方法.
- 这项技术提供了一种简单有效的解决方案,用于快速地在现场对TCM中的SO2残留物进行质量控制.
- 开发的传感器平台有望用于超越TCM分析的各种定量气体传感应用.
相关概念视频
Atomic Absorption Spectroscopy: Lab
389
For AAS measurements, samples must be introduced as clear solutions, often requiring extensive preliminary treatment to dissolve materials like soils, animal tissues, and minerals. Common methods for sample preparation include treatment with hot mineral acids, wet ashing, combustion in closed containers, high-temperature ashing, or fusion with reagents.
Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing...
Solutions containing organic solvents, such as low-molecular-mass alcohols, esters, or ketones, enhance absorbances by increasing...
389
Raman Spectroscopy Instrumentation: Overview
372
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
372
Atomic Absorption Spectroscopy: Overview
2.1K
Atomic absorption spectroscopy (AAS) is a technique used to analyze elements by measuring electromagnetic radiation (EMR) absorbed by atoms, which causes them to transition to a higher-energy orbit. The most crucial step in AAS is atomization, where the analyte is converted into gas-phase atoms, typically through a flame or furnace. Some of these atoms become thermally excited in the flame, while most remain in the ground state.
When irradiated by EMR of a particular wavelength, these...
When irradiated by EMR of a particular wavelength, these...
2.1K
![Quantitative SERS Detection of Uric Acid via Formation of Precise Plasmonic Nanojunctions within Aggregates of Gold Nanoparticles and Cucurbit[n]uril](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F61682.jpg&w=3840&q=50)

