血流风险的种族差异:一项生态流行病学研究,比较韩国和英国的受试者
Dong-Seon Kang1, Pil-Sung Yang2, Daehoon Kim1
1Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Thrombosis and haemostasis
|February 15, 2024
概括
这项研究发现,东亚人的整体出血发病率低于白人,但内出血和呼吸道出血的发病率更高. 饮酒等生活方式因素影响出血风险的种族差异.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 遗传学 是一个遗传学.
背景情况:
- 调查健康结果的种族差异对于公平的医疗保健至关重要.
- 以前的研究表明,不同种族群体的出血倾向存在差异.
研究的目的:
- 为了比较东亚和高加索人口之间的出血发生率.
- 为了确定特定的出血类型和与种族相关的影响因素.
主要方法:
- 生态流行病学研究设计.
- 利用来自韩国国家健康保险服务-健康查和英国生物银行 (2006-2010) 的数据.
- 包括健康的参与者,分析了112,750名东亚人和210,995名高加索人的主要结局,包括内出血和全身出血.
主要成果:
- 与高加索人相比,东亚人对整体出血的5年发病率降低了38%.
- 在东亚人中较低的重大出血,胃肠道和泌尿器出血率.
- 在东亚人中观察到内出血 (ICH) 和呼吸道出血的发病率较高.
- 与高加索人相比,东亚的酒精消费者 (每周≥3次) 的初级结局发病率增加.
结论:
- 在出血发生率上存在显著的种族差异,因解剖部位而异.
- 生活方式因素,如酒精消耗,在调节跨种族出血风险方面发挥作用.
- 建议根据种族和生活方式量身定制的医疗管理策略来解决出血风险.
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