对暴露于幻觉剂的患者进行外科手术期间的考虑
Trent Emerick1, Tetyana Marshall2, Thomas Jeff Martin3
1Department of Anesthesiology and Perioperative Medicine, Chronic Pain Division, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA emericktd@upmc.edu.
幻觉剂和迷幻药物暴露会影响麻醉护理. 了解这些物质.
科学领域:
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
- 毒理学 毒理学 毒理学
背景情况:
- 幻觉剂和迷幻药物暴露在外科手术期间的护理中带来了独特的挑战.
- 急性和慢性暴露可以改变患者的生理学,影响麻醉和止痛疗效.
- 幻觉剂使用率的上升需要全面了解安全的患者管理.
研究的目的:
- 审查各种各样的幻觉剂和迷幻药.
- 阐明它们的潜在周围操作影响和管理考虑.
- 为了教育麻醉提供者如何优化对暴露患者的护理.
主要方法:
- 对现有关于幻觉剂和迷幻药物的文献进行了叙事审查.
- 审查重点关注可能影响术后管理的物质.
- 分析了作用机制和受体相互作用.
主要成果:
- 幻觉剂和迷幻药具有不同的作用机制.
- 常见的作用包括调节血清路径 (增加水平或受体活性).
- 其他机制包括N-甲基-D-阿斯巴达酸盐受体对抗和肌肉酸受体刺激.
结论:
- 幻觉剂的各种药理特征需要个性化的外科手术期间策略.
- 麻醉提供者必须意识到潜在的药物相互作用和生理影响.
- 有信息的管理对于减轻患有幻觉毒素暴露的患者的风险至关重要.
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