通过微波助力深度环氧溶剂提取的日期残渣多糖的肠道微生物群调节,益生菌和生物活性特征
Gafar Babatunde Bamigbade1, Athira Jayasree Subhash1, Basel Al-Ramadi2
1Department of Food Science, College of Agriculture and Veterinary Medicine, United Arab Emirates University (UAEU), Al-Ain, United Arab Emirates.
International journal of biological macromolecules
|February 15, 2024
概括
枣子残渣多糖 (MPS) 具有强大的抗氧化和酶抑制特性. 这些日片纤维对肠道微生物群的组成有积极的影响,并显示出有前途的抗菌和抗增殖作用.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物化学 生化学
- 微生物学 微生物学
背景情况:
- 枣子是生物活性化合物的丰富来源,包括多糖.
- 食品废弃物的价值化,如日,可以导致新的功能成分.
- 了解枣残渣多糖 (MPS) 的健康益处对于其应用至关重要.
研究的目的:
- 用微波助力深层欧性溶剂从日片中提取的MPS的特征.
- 评估MPS的体外抗氧化,酶抑制,抗增殖和抗菌活动.
- 研究MPS对肠道微生物群组成和益生菌生长的影响.
主要方法:
- 微波辅助提取使用深深的浸泡溶剂进行MPS隔离.
- 在体外测定抗氧化活性 (DPPH,ABTS),酶抑制 (α-amylase,α-glucosidase,ACE) 和抗增殖作用 (Caco-2,MCF-7细胞).
- 在体外分析MPS对肠道微生物群和益生菌生长的影响,包括对物种相关性的网络分析.
主要成果:
- MPS表现出显著的抗氧化活性 (DPPH:57.0%,ABTS:66.4%) 和酶抑制 (α-氨酶:77% ,α-葡萄糖酶:80%,ACE:43%).
- MPS对Caco-2 (100%) 和MCF-7 (99%) 细胞表现出强烈的抗增殖作用以及广泛的抗菌特性.
- MPS与有益的肠道细菌 (例如Bifidobacterium longum) 有正相关,表明短链脂肪酸 (SCFA) 生产增加,而与潜在有害细菌有负相关.
结论:
- 枣子多糖具有显著的功能性质,包括抗氧化,抗糖尿病,抗高血压和抗癌潜力.
- MPS积极调节肠道微生物群的组成,促进有益的细菌,并可能增强SCFA的生产.
- 枣子可以被认为是有价值的食纤维来源,具有相当大的促进健康的益处.
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