透视胆囊支架,以预防延迟胆囊切除术中的复发胆囊炎:一项随机试验
Wiriyaporn Ridtitid1, Julalak Karuehardsuwan1, Natee Faknak1
1Division of Gastroenterology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; Excellence Center for Gastrointestinal Endoscopy, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Gastroenterology
|February 15, 2024
概括
在等待手术的患者中,内透皮胆囊支架 (ETGS) 显著减少了复发性胆囊炎. 这种干预措施在预防复发方面被证明是有效的,特别是在程序后的最初三个月内.
科学领域:
- 胃肠病学 胃肠病学
- 手术创新 在外科创新.
- 临床结果研究研究
背景情况:
- 治疗急性胆囊炎往往需要推迟手术.
- 内透皮胆囊支架 (ETGS) 是对选定患者的辅助疗法.
- 以前缺乏ETGS结果的比较数据.
研究的目的:
- 为了比较3个月和6个月的复发性胆囊炎的发病率.
- 评估ETGS在推迟胆囊切除术患者的疗效.
- 评估ETGS作为急性胆囊炎的干预措施.
主要方法:
- 随机对照试验涉及120名患有急性结石胆囊炎和高概率的普通胆道结石的患者.
- 组A获得了ETGS;组B没有. 后来,两组人都接受了胆囊切除术.
- 进行了治疗意向分析.
主要成果:
- 组A (ETGS) 显示3个月的复发率明显较低 (0%对18.3%,P=.001).
- ETGS的技术和临床成功率分别为90%和100%.
- 在A组3-6个月之间观察到非显著较低的复发率 (0%对10%,P=.11).
结论:
- 当胆囊切除术推迟时,ETGS有效地预防了复发性胆囊炎.
- 在未经凝固的群体中,复发主要发生在3个月内.
- 在特定患者群体中,ETGS是治疗急性胆囊炎的可行选择.
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