在老年人中对抗微生物药物管理的挑战
Joana Alves1, Virginie Prendki2, Marie Chedid3
1Infectious Diseases Specialist, Head of Local Unit of the Program for Prevention and Control of Infection and Antimicrobial Resistance, Hospital de Braga, Portugal.
European journal of internal medicine
|February 15, 2024
概括
对于老年人,特别是那些患有多种健康状况的人来说,抗生素管理 (ASM) 策略至关重要,以减少感染风险和抗生素副作用. 更新的指南和干预措施改善了医院和长期护理机构的患者护理.
科学领域:
- 老年病的医生 老年病的医生
- 传染性疾病 传染性疾病
- 内部医学 内部医学
背景情况:
- 越来越多的老年人住院和长期护理设施 (LTCF).
- 患有多种疾病的老年人面临更高的感染风险和抗生素不良影响.
- 对于这种人群的抗微生物药物管理 (ASM) 有有限的研究和指导方针.
研究的目的:
- 解决对老年人有效和更安全的抗微生物管理 (ASM) 策略的需求.
- 更新优化老年人抗菌素处方的策略.
- 建议在长期护理机构中为ASM提供框架.
主要方法:
- 对老年人ASM现有文献的综述.
- 识别成功的ASM干预措施 (例如快速诊断,生物标志物,降级,IV到口服切换).
- 关于LTCF的五个领域ASM框架的建议.
主要成果:
- ASM干预与减少副作用,降低死亡率,缩短住院时间和降低成本有关.
- 像快速诊断和降级等特定策略是有效的.
- 一个结构化的框架可以指导在LTCF中ASM的实施.
结论:
- 有效的抗菌药物管理 (ASM) 对住院的老年人和LTCF患者至关重要.
- 多学科合作 (内科医生,老年医生,药剂师,传染病专家) 是关键.
- 更新的策略和结构化的框架可以改善老年患者的护理和治疗结果.
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