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Updated: Jul 3, 2025

In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells
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Published on: September 2, 2019

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在核糖体中,Chp1是一个专门的伴侣,它保证了eEF1A生物发生

Melania Minoia1, Jany Quintana-Cordero1, Katharina Jetzinger1,2

  • 1Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm, Sweden.

Nature communications
|February 15, 2024
PubMed
概括

一个新发现的伴侣,Chp1,在合成过程中对于真核细胞翻译延长因子1A (eEF1A) 的正确折叠至关重要. 没有Chp1,细胞经历蛋白质稳定性崩,但Chp1也可以防止与疾病相关的eEF1A变异.

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