后COVID状态下高压氧气治疗的长期结果:随机对照试验的纵向随访
Amir Hadanny1,2, Shani Zilberman-Itskovich3,4, Merav Catalogna3
1Sagol Center for Hyperbaric Medicine and Research, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel. amir.had@gmail.com.
Scientific reports
|February 15, 2024
概括
高压氧疗法 (HBOT) 显著改善了长期的COVID症状,包括认知,睡眠和疼痛问题. 这些好处在治疗后至少持续一年,提高了患者的生活质量.
科学领域:
- 神经学 神经学
- 肺部病理学 肺部病理学
- 康复医学 康复医学 康复医学
背景情况:
- 长期COVID综合征呈现持续的认知,精神,疲劳,睡眠和疼痛症状.
- 之前的研究表明,高压氧气疗法 (HBOT) 对这些症状有短期益处.
研究的目的:
- 评估HBOT对长期COVID综合征患者的长期 (1年) 影响.
- 评估HBOT诱导的改善生活质量,睡眠,神经精神和疼痛症状的持久性.
主要方法:
- 一项31名患有COVID-19后认知症状的患者的纵向随访研究.
- 患者每天接受40次HBOT治疗.
- 评估发生在最后一次HBOT会话后一年,使用SF-36和BSI-18问卷进行评估.
主要成果:
- 在大多数SF-36领域,长期改善生活质量与短期结果相比较.
- 改善睡眠质量的持续中度效果大小 (ES1=0.47-0.79).
- 对于神经精神病症状改善 (BSI-18) 和疼痛严重程度 (ES1=0.69) 和干扰 (ES1=0.83) 的长期显著减少,持续的大效果大小.
结论:
- 高压氧气疗法对长期的COVID症状表现出持续的积极影响.
- 在长期的COVID患者中,HBOT改善了生活质量,睡眠质量,并减少了神经精神病和疼痛症状.
- 对HBOT的临床益处在治疗后至少维持一年.
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