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Updated: Jul 3, 2025

Laser Microirradiation to Study In Vivo Cellular Responses to Simple and Complex DNA Damage
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Published on: January 31, 2018

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缺少PARG的瘤细胞对EXO1/FEN1介导的DNA修复的依赖性增加

Christina Andronikou1,2,3,4, Kamila Burdova5, Diego Dibitetto1,4

  • 1Institute of Animal Pathology, Vetsuisse Faculty, University of Bern, 3012, Bern, Switzerland.

The EMBO journal
|February 15, 2024
PubMed
概括

向多ADP-糖糖酶 (PARG) 揭示了癌细胞中的新漏洞. 抑制EXO1/FEN1在治疗抗PARPi和BRCA2缺乏的瘤方面显示出有前途.

关键词:
这就是BRCA2的原因.修复DNA修复DNA的修复时间 EXO1 EXO1这就是FEN1的原因.在巴黎的公园里

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