糖尿病对腰椎退化的影响:基于MRI的研究
Xiaoming Tian1, Hongwei Zhao2, Sidong Yang3
1Department of Spinal Surgery, Hebei Medical University Third Hospital, 139 Ziqiang Road, Shijiazhuang, 050051, Hebei, China.
概括
糖尿病 (DM) 显著加速脊椎退化,增加盘退化和准脊椎肌肉中的脂肪透. 无法控制的高血糖 (高血糖) 与腰椎的这些不良放射性变化有关.
科学领域:
- 放射学 放射学是一门学科.
- 内分泌学 在内分泌学.
- 整形外科 整形外科 整形外科
背景情况:
- 糖尿病是一种复杂的代谢障碍,具有广泛的全身影响.
- 脊椎退化,包括椎间盘和椎肌肉变化,是腰部疼痛的常见原因.
- 脊髓病对脊髓退化的影响需要使用先进的成像技术进行进一步的研究.
研究的目的:
- 分析2型糖尿病 (T2DM) 对腰椎间盘和椎肌肉的放射性变化的影响.
- 为了研究长期不受控制的高血糖和脊髓退化之间的关联.
- 评估基于MRI的脊柱退行指标,在T2DM和没有T2DM的患者.
主要方法:
- 对186名患有腰椎间盘的患者 (98名T2DM患者,88名对照患者) 的回顾性分析,与关键特征相匹配.
- 收集的数据包括人口统计,并发症和MRI扫描的放射性参数.
- 评估的放射性参数是圆盘高度,修改的Pfirrmann分级,准脊椎肌肉脂肪透和端板病理.
主要成果:
- 与对照组相比,T2DM患者在所有腰部段 (L1-S1) 中表现出明显更大的椎间盘退化.
- 在T2DM组,L4/5和L5/S1准脊椎肌肉中脂肪透的百分比较高.
- 软骨末端板的病理变化在T2DM组中更为普遍.
结论:
- 在T2DM中,长期的,控制不良的高血糖症与加速的腰椎盘退化有关.
- 在T2DM患者中,腰椎下部准脊椎肌肉的脂肪透更为常见.
- 端板软骨病理变化的发病率增加与T2DM有关,这表明它在退行性磁盘疾病进展中发挥了作用.
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