月经周期对血液动力学和自主反应对中央低血压的影响
Vishwajeet Shankhwar1, Janez Urvec2, Bianca Steuber3
1College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Frontiers in cardiovascular medicine
|February 16, 2024
概括
月经阶段会影响低血压期间的自主反应. 黄质阶段表现出更高的交感活动和心血管反应,可能是由于雌激素水平升高.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统的调节规则
- 生殖内分泌学 生殖内分泌学
背景情况:
- 月经周期的不同阶段会改变雌激素和孕激素水平.
- 关于月经阶段对心血管和自主调节在低血压期间的影响现有的研究是相互矛盾的.
研究的目的:
- 研究月经阶段对心血管和自主反应的影响.
- 用下体负压 (LBNP) 来分析休息期间的反应和实验性诱导的中央低血压.
主要方法:
- 评估了14名健康的女性 (8个卵泡,6个质阶段).
- 在休息,LBNP和恢复期间测量出血动力学和心率变化 (HRV).
- 收集血液样本以确定雌激素和孕水平.
主要成果:
- 阶段之间的静止血液动力学变量没有显著差异.
- 毛囊阶段显示较低的静止低频 (LF) 和较高的高频 (HF) 功率,与形阶段相比.
- 仅在毛囊阶段观察到对低血压的自主反应 (LF和HF功率的变化).
结论:
- 月经阶段会影响休息自主功能,在黄质阶段交感活动较高.
- 中枢低血压症会加剧心血管和自主反应,特别是在质期.
- 雌激素水平升高和交感活性增加可能解释低血压期间的质期反应.
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