与怀孕相关的急性损伤的风险因素和胎儿的结果
Shipra Sandilya1, Kumari Usha Rani1, Rajesh Kumar2
1Department of Obstetrics and Gynaecology, V.M.M.C. and Safdarjung Hospital, New Delhi, Delhi, India.
Journal of family medicine and primary care
|February 16, 2024
概括
与怀孕相关的急性损伤 (PRAKI) 是一种严重的疾病,通常是由可预防的因素引起的,如先兆子和败血症. 早期检测和管理对于改善PRAKI病例中母亲和胎儿的结果至关重要.
科学领域:
- 产科和妇科 产科和妇科
- 腎臟病學 (nephrology) 是一種醫學專業.
- 公共卫生 公共卫生
背景情况:
- 与怀孕相关的急性损伤 (PRAKI) 是一种影响怀孕,分娩和产后功能的关键并发症.
- 在像印度这样的地区,由于对三级医疗保健的获取有限,需要了解各种分娩环境中的风险因素和结果.
- 及时诊断和干预对于减轻PRAKI及其严重后果至关重要.
研究的目的:
- 调查导致PRAKI的主要孕产妇风险因素.
- 为了评估被诊断患有PRAKI的患者的胎儿与母亲的结局.
- 确定怀孕护理中预防策略的关键领域.
主要方法:
- 一项从2021-2022年进行的前性研究,涉及50名符合AKIKDIGO标准的孕妇和产后妇女.
- 利用包括CBC,血清电解质,连续KFT,尿液输出和USG-KUB.UB在内的综合监测.
- 干预包括透析,如果有指示,与的恢复定义的血清肌水平在六周内.
主要成果:
- 大多数PRAKI病例 (54%) 发生在21-25岁的未预约患者中,来自较低的社会经济背景.
- 确定的主要危险因素是孕前 (28%),产后败血症 (24%) 和产后出血 (PPH) (20%).
- 在80%的患者中观察到完全的恢复,尽管产妇死亡率为14%,主要是由于败血症和孕前的并发症. 胎儿结局包括76%的活产,24%的子宫内死亡.
结论:
- 可预防的疾病,如孕前症,产后败血症和PPH是PRAKI最重要的危险因素.
- 对这些产科紧急情况的有效管理可以大大减少PRAKI的发生率和严重程度.
- 改善获得护理的机会和早期识别高风险怀孕对于更好的孕产妇和胎儿健康至关重要.
相关概念视频
01:17Factors Affecting Renal Clearance: Renal Impairment
94
Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
94
01:11Renal Failure: Dose Adjustments
89
In patients with renal impairment, drugs undergo significant changes in their pharmacokinetics, which require dosage adjustments to ensure safe and effective therapy.
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
Reduced renal clearance and elimination rate are common outcomes of renal impairment. These alterations lead to a prolonged elimination half-life and an altered apparent volume of distribution for drugs. As a result, dosage adjustments are typically necessary to maintain optimal drug levels in the body.
However, dosage adjustments...
89
01:07Teratogenicity
2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
01:27Dialysis
309
Renal failure occurs when the kidneys lose their ability to filter waste products from the blood effectively. It can be classified into two types: acute renal failure (ARF) and chronic renal failure (CRF).
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
Acute kidney injury develops suddenly and can be caused by pre-renal causes (e.g., hypovolemia, shock), intrinsic renal causes (e.g., acute tubular necrosis), or post-renal causes (e.g., urinary obstruction). In contrast, chronic renal failure progresses gradually over time and is often...
309
01:10Nephrons
2.4K
The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
2.4K
01:21External Anatomy of the Kidney
1.1K
The kidneys are a pair of bean-shaped organs in the human body that play a critical role in maintaining overall health. They filter out waste products from the blood, regulate blood pressure, maintain electrolyte balance, and stimulate the production of red blood cells.
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
1.1K