早期治疗将防止怀孕期间甲状腺疾病的胎儿-母亲并发症:一项前性研究
Smruti Vaishnav1, Dharak Pandya2, Rama Shrivastava1
1Obstetrics and Gynaecology Department, Pramukhswami Medical College and Shree Krishna Hospital, Bhaikaka University, Karamsad, Anand, Gujarat, India.
Journal of family medicine and primary care
|February 16, 2024
概括
甲状腺疾病影响了23.5%的孕妇,增加了诸如子宫前等风险. 在怀孕期间早期查和治疗甲状腺功能障碍对于预防不良的胎儿-母亲结果至关重要.
科学领域:
- 内分泌学 在内分泌学.
- 产科 产科 产科 产科 产科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
背景情况:
- 怀孕期间的甲状腺疾病与母亲和胎儿的不良结果有关.
- 及时识别和治疗对于管理这些风险至关重要.
- 印度患有大量未诊断的甲状腺疾病,加剧了胎儿与母亲之间的并发症.
研究的目的:
- 为了确定在农村的第三级护理环境中孕妇甲状腺疾病的患病率.
- 评估甲状腺功能障碍与胎儿与母亲并发症之间的关联.
- 强调早期查和治疗怀孕期间甲状腺疾病的重要性.
主要方法:
- 一项前性研究包括350名孕妇在他们的第一季度.
- 进行了甲状腺功能测试 (TSH,FT3,FT4),并根据ATA指南治疗疾病.
- 在整个怀孕期间,对母亲和胎儿的结果进行了监测.
主要成果:
- 在23.5%的孕妇中发现甲状腺疾病,甲状腺功能低下是最常见的 (20%).
- 甲状腺功能低下症与妊娠前的风险增加显著相关 (P=0.004).
- 虽然趋势表明甲状腺功能低下的母亲的堕胎和胎儿死亡率更高,但这些并没有统计学意义 (P=0.07).
结论:
- 建议在怀孕早期进行普遍的甲状腺查,特别是在资源有限的环境中.
- 早期检测和在前10周内进行治疗可以预防严重的孕产妇和胎儿并发症.
- 患有甲状腺功能低下症的孕妇需要密切监测孕前.
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